Boosting Human Growth Hormone Naturally With Supplements

boosting human growth hormoneBoosting human growth hormone naturally can be as simple as taking inexpensive supplements combined with exercise and sleep.  This is the continuation of Better Body After 50: Boosting Growth Hormone Part 1.

Nutritional Supplements for Natural HGH Release

Boosting Human Growth Hormone with Amino Acids

Twenty amino acids form the building blocks of all proteins in your body. You use these proteins to make muscle, bone, enzymes, skin, and many hormones. Some amino acids are essential meaning the body cannot produce them on its own. These amino acids must come from the foods you eat.

Tests show that certain amino acids induce growth hormone secretion. And for most people, simply supplementing the diet with these amino acids will elevate growth hormone levels.

Advantages are – they’re easy to take, usually free from side effects, safe, readily available at a health food store or online, and cheap (costing less than $1 per day).

The key to boosting human growth hormone comes from – timing (when you take them), quantity (how much to take), and selection (which amino acids to take).


Arginine is an essential amino acid, meaning your body can’t produce this on its own.

Effect on HGH – Arginine (also written as L-arginine) is a proven growth hormone releaser. In the book by researchers Sandy Shaw and Dirk Pearson called Life Extension: A Practical Scientific Approach, arginine and ornithine are tested as HGH releasers. Shaw took 10 grams of arginine each day on an empty stomach to release growth hormone and speed up the healing of her broken foot. About an hour after taking the arginine, she did 3 minutes of bench presses.

That’s all! In 6 weeks she reportedly lost 25 lbs. of fat and gained 5 lbs. of muscle.  Researchers have conducted several studies on the effects of arginine on growth hormone release. Several doses were used in these studies, with .28 grams per kilogram of body weight (12 grams of arginine for a 165 lb. person) showing the most results.

And based on studies with an older population, arginine keeps working into old age. Subjects in their 70s had lower response than younger subjects but still showed arginine boosted their growth hormone level to 3 times the average for their group!

Boosting Human Growth Hormone With Arginine

By boosting human growth hormone, arginine increases fat burning and muscle building, boosting immunity, fighting cancer, promoting wound healing, protecting the liver, and restoring sexual function in impotent men.

How it works – arginine stimulates the release of growth hormone by blocking somatostatin, a growth hormone inhibitor. Somatostatin increases as we age and inhibits the release of growth hormone. Arginine affects sexual function is the result of being a precursor to Nitric Oxide (NO), which helps initiate and maintain erections.

Dosage – Typical dose is 2 to 5 grams on an empty stomach taken one hour prior to exercise and 1 hour prior to bedtime. That’s 4 to 10 grams per day.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – the dosage needed for boosting human growth hormone can cause stomach upset (needs to be taken on an empty stomach). Starting with only 1 gram and raising the dosage each day until you reach the recommended amount can eliminate any stomach upset.


As mentioned earlier, arginine is a proven growth hormone releaser. It also converts to nitric oxide which can improve blood vessel elasticity leading to better cardiovascular health and erections. However, another amino acid, citrulline, may be even more effective. Citrulline metabolizes into arginine. So if you’re after arginine why take citrulline? Citrulline absorbs into the body better. With a smaller dose, you get the benefits of arginine.

Recent studies show taking citrulline along with arginine may provide a better effect than arginine alone. The best way to find out is to take each separately then together.

Dosage – 1 gram daily.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – At recommended doses, citrulline shows no reported toxicity or adverse side effects.


Ornithine is a nonessential amino acid, meaning your body can create this amino acid.

Effect on HGH – In the same work by Pearson and Shaw, they found ornithine to be twice as effective at arginine … and at twice the cost too. Their studies showed growth hormone release from taking 5 -10 grams of arginine and 2.5 – 5 grams or ornithine on an empty stomach prior to going to bed.

Usage – Ornithine is best used in combination with other amino acids like arginine, glutamine, and lysine. * See Stacking Amino Acids.

Dosage – Typical dose is 2 to 5 grams on an empty stomach taken at bedtime.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – at high doses (170 milligrams per kilogram of bodyweight or 12 grams for a 165 lb. person) subjects experienced runny, watery diarrhea.


Lysine is another essential amino acid. It affects height, bones, and genital function.

Effect on HGH – A study by A. Isadori, M.D., showed growth hormone increase in a group of 15 to 20 year olds taking only 1.2 grams of lysine and 1.2 grams of arginine pyroglutamate once a day. Studies on men over 65 did not show any effect at these lower doses.

Anti-aging – One researcher notes evidence that lysine and arginine used together increases thymic hormone secretion in older humans and animals, perhaps partially reversing age related immune deficiency. This could be related to boosting human growth hormone. Also, in a Mayo Clinic study, lysine reduced the recurrence of herpes simplex infections when taken at a dose of 1.25 grams.

Usage – Lysine, like ornithine, may have the best effect when taken in combination with other amino acids like arginine, glutamine, and ornithine. * See Stacking Amino Acids.

Dosage – 1 gram on an empty stomach taken 1 hour before bedtime and exercise.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – Lysine should have no side effects at recommended doses. At high doses, subjects experienced diarrhea.


Glutamine is the amino acid most used by our bodies. It prevents muscle wasting especially during times of stress. Glutamine is the primary energy source for the immune system.

A study in 1994 showed high levels of glutamine in the blood spelled greater overall health. Subjects in the study who had high glutamine levels had fewer illnesses, lower blood pressure, lower cholesterol, and were closer to their ideal weight than subjects with low glutamine. The lower glutamine group had more higher rates of heart disease, diabetes, and arthritis.

Effect on HGH – A study by Thomas Welbourne showed that a small dose of glutamine – 2 grams – raised growth hormone levels 4 times more than a placebo. The ages of the subjects ranged from 32 to 64.

Usage – Glutamine comes in pills and powder form. Vincent Giampapa, M.D. (world renowned for leadership in natural hormone replacement), says 2 grams of glutamine has more effect than the combined effect of 1 gram each of arginine, ornithine, and lysine. Still, best results seem to come from a combination of amino acids. * See Stacking Amino Acids.

Dosage – 2 grams on an empty stomach taken 1 hour before bedtime and exercise.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – Glutamine has virtually no negative effects at recommended dosage.

OKG (L-ornithine Alpha-Ketoglutarate)

OKG is technically not an amino acid. It is, however, the amino acid ornithine bound to alpha ketoglutarate, which is a precursor to glutamine. L-ornithine Alpha-Ketoglutarate can boost human growth hormone. OKG actually boosts glutamine levels in the blood more than glutamine itself does!

This substance originated in France and is used there to rebuild body tissue after burns, trauma, and surgery. It actually has strong anabolic effects in the body.

Effect on HGH – OKG is shown to boost growth hormone levels in doses of 10 grams or more, more so than ornithine or alpha ketoglutarate individually.

Dosage – 10 grams taken with fluids.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – OKG has not been tested much outside of France. Taken with fluids, it is well tolerated.


Glycine is a nonessential amino acid and, for some reason, has been largely overlooked for boosting human growth hormone. But research has shown effects from a 3 fold increase to a 10 fold increase in serum growth hormone levels.

Effect on HGH – Glycine stimulates the pituitary gland to secrete HGH.

Dosage – 250 milligrams to 6.75 grams.

* See important note on “cycling” HGH releasers later in this section.

Side Effects – At recommended doses, glycine shows no reported toxicity or adverse side effects.

arginine solutionStacking Amino Acids for Boosting Human Growth Hormone

You get the best growth hormone release from a combination or “stack” of the amino acids arginine, ornithine, lysine, and glutamine. Take these together at bedtime.  The raised level of growth hormone effectively keeps your body from breaking down as much muscle as it normally would during the 7 hours of so of fasting and resting.

Through research, Dr. Giampapa has seen the benefits of hundreds of individuals following a plan of growth hormone releasers. Here’s his recommendation for stacking:

Beginners Stack – 2 grams arginine, 2 grams ornithine, 1 gram lysine, and 1 gram glutamine. You should see a small to moderate effect. Then increase it to . . .

Effective Stack – 2 grams arginine, 2 grams ornithine, 2 grams lysine, and 2 grams glutamine. This should have a noticeable effect on growth hormone secretion.

Insulin Effect

An additional benefit of this amino acid stack is that it raises insulin. Insulin levels are usually falling when growth hormone is rising. However, if you increase insulin even a small amount when growth hormone levels are high, you get a strong anabolic effect (muscle building).

Insulin increases the rate at which amino acids enter muscle. Growth hormone stimulates protein synthesis. Combined, these two actions produce what’s needed to incorporate amino acids into protein and subsequently build muscle.

Dr. Di Pasquale recommends a stack of amino acids taken at bedtime as follows:

Di Pasquale Stack – 3 grams arginine, 3 grams glutamine, 3 grams lysine at bedtime each night, and adding 1 gram of each per week until you are taking 5 grams each.

This stack should produce, according to Di Pasquale, a 10 to 20% increase in growth hormone. But a seemingly small increase in growth hormone can actually have a marked effect on IGF-1 (Insulin-like Growth Factor-1) and show the results you were aiming for.

Continue reading Better Body After 50: Boosting Human Growth Hormone Part 1 – More HGH Releasers.